Presents as small, 'confetti-like' white macules on sun-exposed areas, particularly the shins, in older individuals.
Causes atrophic, white plaques that can resemble vitiligo, but the skin texture is thinned and wrinkled ('cigarette paper').
A central, pigmented nevus surrounded by a symmetric ring of depigmentation, representing an immune response to the mole.
A variant of cutaneous T-cell lymphoma presenting as hypopigmented patches, often with fine scale or atrophy, and a positive biopsy.
This medication can cause pigmentary dilution or depigmentation, which is distinguished by the clear history of drug initiation.
Tuberculoid leprosy presents as well-demarcated, hypopigmented patches that are characteristically anesthetic (lacking sensation).
A congenital, stable, off-white patch of hypopigmentation that is present from birth or early childhood and does not progress.
A parasitic infection ('river blindness') that can cause 'leopard skin' depigmentation, particularly on the shins, in endemic areas.
A congenital genetic disorder characterized by a stable, symmetric white forelock and depigmented patches on the central trunk and limbs.
Presents as ill-defined, hypopigmented patches with a fine scale, typically on the face of children and often associated with atopy.
A fungal infection causing hypo- or hyperpigmented macules with a fine scale that is evident on stretching the skin, confirmed by KOH prep.
Areas of decreased pigment that occur at the site of a previous inflammatory process (e.g., eczema, psoriasis), with a clear history of a prior rash.
Morphea can cause hypopigmentation, but it occurs within an indurated, firm plaque of sclerotic skin.
