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Eczema

Presents as ill-defined erythema and scale, not the discrete papules from bites, and lacks the visible nits or lice on hair shafts.

Folliculitis

Characterized by pustules centered on hair follicles, which can be bacterial or fungal, unlike the pruritic macules and papules of lice bites.

Lichen simplex

Results from chronic scratching, causing thickened, leathery skin (lichenification), rather than being the primary cause of the itch itself.

Perianal Streptococcus

A bacterial infection causing bright, beefy-red, well-demarcated erythema, confirmed by culture, unlike the presentation of parasitic infestation.

Scabies

Caused by a mite that burrows into the skin, creating linear burrows, and typically causes more widespread and intense nocturnal pruritus than pubic lice.

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