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Contact dermatitis

Allergic contact dermatitis from a plant (phytodermatitis) can be photosensitive, but it follows the pattern of contact with the plant, not just general sun exposure.

Dermatomyositis

The rash of dermatomyositis is a persistent, violaceous erythema with specific signs (Gottron, heliotrope), not a transient, recurrent, itchy eruption like PLE.

Drug phototoxicity

This is a painful, exaggerated sunburn reaction to a drug, whereas PLE is an idiopathic, delayed, and pruritic papular eruption.

Eczema

While some eczema is photosensitive, PLE is distinguished by its acute, transient nature, appearing only after sun exposure and resolving completely.

Perioral dermatitis

This is a chronic papular eruption around the mouth, not a transient, sun-induced rash.

Rosacea

Rosacea is a chronic condition of flushing and papules that is exacerbated by sun, but it does not appear and disappear in the acute, recurrent pattern of PLE.

Subacute lupus erythematosis

The lesions of SCLE are persistent, annular, or papulosquamous plaques, not the transient papules of PLE, and are associated with specific autoantibodies (anti-Ro).

Sunburn

A sunburn is a painful, uniform erythema that occurs shortly after exposure, whereas PLE is typically a delayed, pruritic, papular eruption.

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