This is a perforating dermatosis characterized by keratotic plugs within crater-like papules, a different morphology than the excoriated, dome-shaped nodules of prurigo nodularis.
This is a low-grade lymphoma characterized by recurrent crops of papules and nodules that spontaneously ulcerate and heal with scarring.
This is a systemic disease with destructive arthritis and reddish-brown "coral bead" nodules, not the intensely itchy, excoriated nodules of prurigo.
These are waxy, non-pruritic nodules composed of amyloid deposits, whereas prurigo nodules are intensely itchy and are a reactive process.
This is a variant of bullous pemphigoid where the intense itch leads to the formation of prurigo nodules; it is distinguished by immunofluorescence showing antibodies characteristic of pemphigoid.
Cutaneous PAN presents as tender, subcutaneous nodules along the path of arteries, often with livedo reticularis, a different presentation and pathology.
A wart is a verrucous papule caused by HPV, not an intensely itchy, excoriated nodule.