A small nodular BCC can mimic molluscum, but it is typically pearly with telangiectasias and lacks the central umbilication.
Calcinosis cutis lesions are hard, stony deposits, much firmer than the soft, fleshy papules of molluscum.
In an immunocompromised patient, this fungal infection can present with umbilicated papules similar to molluscum, but it is a systemic infection diagnosed by culture or antigen testing.
Similar to cryptococcosis, this systemic fungal infection can cause umbilicated skin lesions in immunocompromised hosts and is diagnosed by culture.
These are yellowish papules related to hypertriglyceridemia, a different color and pathology than the skin-colored, viral papules of molluscum.
This is a benign histiocytosis presenting as a reddish-yellow papule or nodule, typically in an infant, and it lacks central umbilication.
Flat warts are flatter and have a rougher surface than the classic smooth, dome-shaped, umbilicated molluscum papule.
Papular sarcoidosis consists of reddish-brown papules that do not have central umbilication.
These yellowish papules are also umbilicated but are seen in older adults, whereas molluscum is most common in children.
A Spitz nevus is a pink or reddish, dome-shaped papule that lacks central umbilication.
These are multiple, cystic nodules containing oily fluid, not solid, umbilicated papules.
These are small, flat-topped papules around the eyes, lacking the dome shape and central umbilication of molluscum.
A common wart has a rough, verrucous surface, unlike the smooth surface of a molluscum papule.
