This is a single cyst in a specific location (vaginal introitus), unlike HS, which involves multiple, recurrent abscesses and sinus tracts in intertriginous areas.
Cutaneous Crohn's can mimic HS, but it is often associated with "knife-cut" fissures and is linked to underlying gastrointestinal disease.
A pilonidal sinus is a specific condition occurring in the midline of the natal cleft, a different location than the axillary or inguinal sites of HS.