The lupus rash is autoimmune, may be accompanied by systemic symptoms, and persists, whereas drug phototoxicity is a direct sunburn-like reaction that resolves when the drug is stopped.
This is an eczematous, itchy reaction to an airborne allergen, not the painful, sunburn-like erythema of a phototoxic reaction.
This is an autoimmune condition distinguished by its violaceous hue and pathognomonic signs on the eyelids and knuckles, which are absent in drug phototoxicity.
Eczema is a scaly, pruritic dermatitis, not the acute, painful erythema resembling a severe sunburn seen in phototoxicity.
This viral exanthem has a characteristic "slapped cheek" appearance, a different morphology than the confluent erythema of phototoxicity.
PLE is an idiopathic sun allergy with a delayed onset of itchy papules and plaques, whereas drug phototoxicity is a rapid-onset, painful erythema.
Rosacea is a chronic condition of papules, pustules, and flushing, not an acute, confluent, sunburn-like reaction.
This is a chronic, scaly eruption in oily areas, a completely different clinical picture.
This is the most direct mimic, but drug phototoxicity is distinguished by its occurrence with minimal sun exposure in the context of taking a known photosensitizing drug.
