This is a subepidermal blistering disease in a patient with lupus, distinguished by the presence of other lupus criteria and specific autoantibodies.
BP is characterized by large, tense bullae, whereas DH presents with smaller, intensely itchy vesicles that are often excoriated into erosions.
While intensely itchy, eczema presents as scaly patches or plaques, not the primary, grouped vesicles on an erythematous base seen in DH.
This is characterized by classic target lesions, a morphology distinct from the urticarial plaques and grouped vesicles of DH.
Bites cause itchy papules in a random or grouped "breakfast, lunch, dinner" pattern, but lack the classic symmetrical distribution on elbows and knees seen in DH.
This blistering disease is distinguished by its characteristic "string of pearls" or annular arrangement of vesicles and its specific linear IgA pattern on immunofluorescence.
Scabies is identified by its nocturnal pruritus and the presence of burrows, especially in the finger webs, a different clinical picture than the extensor-surface vesicles of DH.
