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Contact dermatitis

Acute contact dermatitis on the legs can cause erythema and edema, but it is differentiated by prominent pruritus and vesicles, and a history of contact with a specific allergen.

Necrobiosis lipoidica

This condition is distinguished by its primary lesion: a waxy, atrophic, yellowish plaque with prominent telangiectasias, which is very different from the spreading erythema of cellulitis.

Stasis dermatitis

While a risk factor for cellulitis, stasis dermatitis itself is a chronic eczematous condition with scaling, lichenification, and brownish discoloration, unlike the acute, warm, and tender plaque of cellulitis.

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