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Congential melanocytic naevus

This is a mole present at or near birth, a key historical feature distinguishing it from an atypical nevus, which is typically acquired later.

Intradermal naevus

This is a benign, raised, often flesh-colored and dome-shaped mole, lacking the asymmetry, border irregularity, and color variation that define an atypical nevus.

Junctional naevus

A simple junctional nevus is a completely flat, small, and uniformly colored macule, whereas an atypical nevus has at least some of the "ABCDE" features of irregularity.

Kaposi's sarcoma

KS presents as purple-to-brownish patches or nodules, a vascular tumor that is morphologically distinct from a melanocytic nevus.

Lentigo

A simple lentigo is a small, uniformly pigmented, and well-demarcated macule, lacking the larger size and irregular features of an atypical nevus.

Lentigo maligna

This is a form of melanoma in situ that presents as a large, slowly enlarging patch on sun-damaged skin, and is generally larger and more variegated than a typical atypical nevus.

Melanoma

While they share features, melanoma is distinguished by demonstrating significant change, growth, or evolution (the "E" in ABCDEs), which is the most critical sign for malignancy.

Melanoma in situ

Similar to melanoma, this is differentiated from a benign atypical nevus by biopsy, but it lacks the uniformity and stability of the other benign nevi.

Naevus spilus

This is a benign lesion characterized by a background café-au-lait patch with multiple darker speckles within it, a unique pattern not seen in a simple atypical nevus.

Pigmented basal cell carcinoma

A pigmented BCC can mimic a dark nevus but is distinguished by classic BCC features like a pearly, rolled border and surface telangiectasias.

Seborrhoiec keratosis

This lesion is distinguished by its waxy, "stuck-on" appearance and can often be gently scraped, a texture very different from a smooth melanocytic nevus.

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