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Alopecia totalis

This is a more severe variant of alopecia areata, distinguished by the complete loss of all scalp hair, whereas classic AA presents as discrete patches.

Central centrifugal cicatricial alopecia

CCCA is a scarring alopecia that starts at the vertex and spreads outward, distinguished by signs of permanent follicular loss (shiny skin, absent pores), unlike the non-scarring nature of AA.

Discoid lupus erythematosis

This is a scarring alopecia characterized by erythematous plaques with follicular plugging and atrophy, confirmed by biopsy, which is different from the smooth, non-inflamed patches of AA.

Morphea

Alopecia from morphea (en coup de sabre) presents as a linear, depressed, indurated plaque on the scalp, a scarring process morphologically distinct from the round patches of AA.

SLE

Hair loss in systemic lupus is typically a diffuse, non-scarring thinning, not the well-demarcated, perfectly smooth patches of alopecia areata.

Syphilis

Secondary syphilis can cause a "moth-eaten" pattern of hair loss with multiple, small, irregular patches, unlike the larger, round/oval patches of classic AA.

Tinea

Tinea capitis is distinguished by the presence of scale, broken hairs ("black dots"), and sometimes inflammation (kerion), all of which are absent in alopecia areata.

Traction alopecia

This is identified by a history of tight hairstyles and hair loss primarily along the frontal and temporal hairlines, with characteristic retained "fringe" hairs.

Trichotillomania

The key finding here is patches of hair of varying lengths due to compulsive pulling, with broken and twisted hairs, unlike the smooth, complete hair loss in an AA patch.

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